8u7u
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Proteasome 20S Core Particle from Beta 3 D205 deletion== | |
| - | + | <StructureSection load='8u7u' size='340' side='right'caption='[[8u7u]], [[Resolution|resolution]] 2.16Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8u7u]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae_S288C Saccharomyces cerevisiae S288C]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8U7U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8U7U FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.16Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8u7u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8u7u OCA], [https://pdbe.org/8u7u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8u7u RCSB], [https://www.ebi.ac.uk/pdbsum/8u7u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8u7u ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PSA5_YEAST PSA5_YEAST] The proteasome degrades poly-ubiquitinated proteins in the cytoplasm and in the nucleus. It is essential for the regulated turnover of proteins and for the removal of misfolded proteins. The proteasome is a multicatalytic proteinase complex that is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. It has an ATP-dependent proteolytic activity. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Saccharomyces cerevisiae S288C]] | ||
| + | [[Category: Blickling M]] | ||
| + | [[Category: Hanna J]] | ||
| + | [[Category: Rawson S]] | ||
| + | [[Category: Razi A]] | ||
| + | [[Category: Velez B]] | ||
| + | [[Category: Walsh Jr RM]] | ||
Revision as of 05:30, 17 April 2024
Proteasome 20S Core Particle from Beta 3 D205 deletion
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