1rna

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[[Image:1rna.gif|left|200px]]
[[Image:1rna.gif|left|200px]]
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{{Structure
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|PDB= 1rna |SIZE=350|CAPTION= <scene name='initialview01'>1rna</scene>, resolution 2.250&Aring;
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The line below this paragraph, containing "STRUCTURE_1rna", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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|GENE=
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|DOMAIN=
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{{STRUCTURE_1rna| PDB=1rna | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rna FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rna OCA], [http://www.ebi.ac.uk/pdbsum/1rna PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1rna RCSB]</span>
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}}
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'''CRYSTALLOGRAPHIC STRUCTURE OF AN RNA HELIX: [U(U-A)6A]2'''
'''CRYSTALLOGRAPHIC STRUCTURE OF AN RNA HELIX: [U(U-A)6A]2'''
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==About this Structure==
==About this Structure==
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1RNA is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RNA OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RNA OCA].
==Reference==
==Reference==
Crystallographic structure of an RNA helix: [U(UA)6A]2., Dock-Bregeon AC, Chevrier B, Podjarny A, Johnson J, de Bear JS, Gough GR, Gilham PT, Moras D, J Mol Biol. 1989 Oct 5;209(3):459-74. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2479753 2479753]
Crystallographic structure of an RNA helix: [U(UA)6A]2., Dock-Bregeon AC, Chevrier B, Podjarny A, Johnson J, de Bear JS, Gough GR, Gilham PT, Moras D, J Mol Biol. 1989 Oct 5;209(3):459-74. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2479753 2479753]
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[[Category: Protein complex]]
 
[[Category: Bear, J S.De.]]
[[Category: Bear, J S.De.]]
[[Category: Chevrier, B.]]
[[Category: Chevrier, B.]]
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[[Category: Moras, D.]]
[[Category: Moras, D.]]
[[Category: Podjarny, A.]]
[[Category: Podjarny, A.]]
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[[Category: a-rna]]
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[[Category: A-rna]]
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[[Category: double helix]]
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[[Category: Double helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 07:41:40 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:30:26 2008''
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Revision as of 04:41, 3 May 2008

Image:1rna.gif

Template:STRUCTURE 1rna

CRYSTALLOGRAPHIC STRUCTURE OF AN RNA HELIX: [U(U-A)6A]2


Overview

The crystallographic structure of the synthetic oligoribonucleotide, U(UA)6A, has been solved at 2.25 A resolution. The crystallographic refinement permitted the identification of 91 solvent molecules, with a final agreement factor of 13%. The molecule is a dimer of 14 base-pairs and shows the typical features of an A-type helix. However, the presence of two kinks causes a divergence from a straight helix. The observed deformation, which is stabilized by a few hydrogen bonds in the crystal packing, could be due to the relatively high (35 degrees C) temperature of crystallization. The complete analysis of the structure is presented. It includes the stacking geometries, the backbone conformation and the solvation.

About this Structure

Full crystallographic information is available from OCA.

Reference

Crystallographic structure of an RNA helix: [U(UA)6A]2., Dock-Bregeon AC, Chevrier B, Podjarny A, Johnson J, de Bear JS, Gough GR, Gilham PT, Moras D, J Mol Biol. 1989 Oct 5;209(3):459-74. PMID:2479753 Page seeded by OCA on Sat May 3 07:41:40 2008

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