1pft
From Proteopedia
(Difference between revisions)
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==N-TERMINAL DOMAIN OF TFIIB, NMR== | ==N-TERMINAL DOMAIN OF TFIIB, NMR== | ||
| - | <StructureSection load='1pft' size='340' side='right'caption='[[1pft | + | <StructureSection load='1pft' size='340' side='right'caption='[[1pft]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1pft]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1pft]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PFT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PFT FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pft FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pft OCA], [https://pdbe.org/1pft PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pft RCSB], [https://www.ebi.ac.uk/pdbsum/1pft PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pft ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/TF2B_PYRFU TF2B_PYRFU] Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre-initiation complex (DNA-TBP-TFIIB). |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pft ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pft ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | The three-dimensional structure of the N-terminal domain of an archaeal TFIIB, which has high sequence homology with eucaryal analogues, is strikingly similar to that of the C-terminal zinc ribbon of the eucaryal transcription elongation factor TFIIB. | ||
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| - | The N-terminal domain of TFIIB from Pyrococcus furiosus forms a zinc ribbon.,Zhu W, Zeng Q, Colangelo CM, Lewis M, Summers MF, Scott RA Nat Struct Biol. 1996 Feb;3(2):122-4. PMID:8564536<ref>PMID:8564536</ref> | ||
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 1pft" style="background-color:#fffaf0;"></div> | ||
==See Also== | ==See Also== | ||
*[[Transcription initiation factors 3D structures|Transcription initiation factors 3D structures]] | *[[Transcription initiation factors 3D structures|Transcription initiation factors 3D structures]] | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Atcc 43587]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Colangelo | + | [[Category: Pyrococcus furiosus]] |
| - | [[Category: Lewis | + | [[Category: Colangelo CM]] |
| - | [[Category: Scott | + | [[Category: Lewis LM]] |
| - | [[Category: Summers | + | [[Category: Scott RA]] |
| - | [[Category: Zeng | + | [[Category: Summers MF]] |
| - | [[Category: Zhu | + | [[Category: Zeng Q]] |
| - | + | [[Category: Zhu W]] | |
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Current revision
N-TERMINAL DOMAIN OF TFIIB, NMR
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