Cullin-associated NEDD8-disassociated protein
From Proteopedia
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| - | <StructureSection load='7z8r' size='340' side='right' caption=' | + | <StructureSection load='7z8r' size='340' side='right' caption='Human CAND1 (yellow) complex with cullin1 (pink) and RBX1 (blue) (PDB id [[7z8r]])' scene=''> |
== Function == | == Function == | ||
Revision as of 08:45, 28 April 2024
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References
- ↑ Pierce NW, Lee JE, Liu X, Sweredoski MJ, Graham RL, Larimore EA, Rome M, Zheng N, Clurman BE, Hess S, Shan SO, Deshaies RJ. Cand1 promotes assembly of new SCF complexes through dynamic exchange of F box proteins. Cell. 2013 Mar 28;153(1):206-15. PMID:23453757 doi:10.1016/j.cell.2013.02.024
- ↑ Cheng W, Yin S, Tu Y, Mei H, Wang Y, Yang Y. SlCAND1, encoding cullin-associated Nedd8-dissociated protein 1, regulates plant height, flowering time, seed germination, and root architecture in tomato. Plant Mol Biol. 2020 Mar;102(4-5):537-551. PMID:31916084 doi:10.1007/s11103-020-00963-7
- ↑ Li X, Zhang Y, Zhao Y, Zhou Y, Han Q, Yang Y, Zhang L, Shi L, Jin X, Zhang R, Gao H, Xue G, Li D, Zhang ZR, Lu Y, Yang B, Pan Z. Cullin-associated and neddylation-dissociated 1 protein (CAND1) governs cardiac hypertrophy and heart failure partially through regulating calcineurin degradation. Pharmacol Res. 2022 Aug;182:106284. PMID:35661710 doi:10.1016/j.phrs.2022.106284
- ↑ Huang X, Liu X, Li X, Zhang Y, Gao J, Yang Y, Jiang Y, Gao H, Sun C, Xuan L, Zhao L, Song J, Bao H, Zhou Z, Li S, Zhang X, Lu Y, Zhong X, Yang B, Pan Z. Cullin-associated and neddylation-dissociated protein 1 (CAND1) alleviates NAFLD by reducing ubiquitinated degradation of ACAA2. Nat Commun. 2023 Aug 1;14(1):4620. PMID:37528093 doi:10.1038/s41467-023-40327-5
