8h6j

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'''Unreleased structure'''
 
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The entry 8h6j is ON HOLD until 2025-04-27
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==Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state.==
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<StructureSection load='8h6j' size='340' side='right'caption='[[8h6j]], [[Resolution|resolution]] 3.25&Aring;' scene=''>
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Authors: Zhang, W., Zhan, X., Zhang, X., Lei, J., Yan, C., Shi, Y.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8h6j]] is a 24 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8H6J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8H6J FirstGlance]. <br>
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Description: Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.25&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=IHP:INOSITOL+HEXAKISPHOSPHATE'>IHP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Zhan, X]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8h6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8h6j OCA], [https://pdbe.org/8h6j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8h6j RCSB], [https://www.ebi.ac.uk/pdbsum/8h6j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8h6j ProSAT]</span></td></tr>
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[[Category: Zhang, W]]
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</table>
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[[Category: Zhang, X]]
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== Function ==
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[[Category: Yan, C]]
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[https://www.uniprot.org/uniprot/SNR40_HUMAN SNR40_HUMAN] Component of the U5 small nuclear ribonucleoprotein (snRNP) complex. The U5 snRNP is part of the spliceosome, a multiprotein complex that catalyzes the removal of introns from pre-messenger RNAs.<ref>PMID:9774689</ref>
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[[Category: Shi, Y]]
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== References ==
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[[Category: Lei, J]]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Lei J]]
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[[Category: Shi Y]]
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[[Category: Yan C]]
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[[Category: Zhan X]]
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[[Category: Zhang W]]
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[[Category: Zhang X]]

Revision as of 06:18, 1 May 2024

Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state.

PDB ID 8h6j

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