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8v2z
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM Structure of Smooth Muscle Gamma Actin (ACTG2) Mutant R257C== | |
| - | + | <StructureSection load='8v2z' size='340' side='right'caption='[[8v2z]], [[Resolution|resolution]] 2.72Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8v2z]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8V2Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8V2Z FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.72Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=HIC:4-METHYL-HISTIDINE'>HIC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8v2z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8v2z OCA], [https://pdbe.org/8v2z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8v2z RCSB], [https://www.ebi.ac.uk/pdbsum/8v2z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8v2z ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/ACTH_HUMAN ACTH_HUMAN] Myopathic intestinal pseudoobstruction;Megacystis-microcolon-intestinal hypoperistalsis syndrome;Familial visceral myopathy. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ACTH_HUMAN ACTH_HUMAN] Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Carman PJ]] | ||
| + | [[Category: Ceron RH]] | ||
| + | [[Category: Dominguez R]] | ||
| + | [[Category: Palmer NJ]] | ||
Current revision
Cryo-EM Structure of Smooth Muscle Gamma Actin (ACTG2) Mutant R257C
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