2l6i
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l6i OCA], [https://pdbe.org/2l6i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l6i RCSB], [https://www.ebi.ac.uk/pdbsum/2l6i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l6i ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l6i OCA], [https://pdbe.org/2l6i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l6i RCSB], [https://www.ebi.ac.uk/pdbsum/2l6i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l6i ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | The transcription and replication of the severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) is regulated by specific viral genome sequences within 5'- and 3'-untranslated regions (5'-UTR and 3'-UTR). Here we report the solution structure of 5'-UTR derived stem-loop 2 (SL2) of SARS-CoV determined by NMR spectroscopy. The highly conserved pentaloop of SL2 is stacked on 5-bp stem and adopts a canonical CUYG tetraloop fold with the 3' nucleotide (U51) flipped out of the stack. The significance of this structure in the context of a previous mutagenesis analysis of SL2 function in replication of the related group 2 coronavirus, mouse hepatitis virus, is discussed. | ||
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| - | The solution structure of coronaviral stem-loop 2 (SL2) reveals a canonical CUYG tetraloop fold.,Lee CW, Li L, Giedroc DP FEBS Lett. 2011 Mar 4. PMID:21382373<ref>PMID:21382373</ref> | ||
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 2l6i" style="background-color:#fffaf0;"></div> | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
Solution structure of coronaviral stem-loop 2 (SL2)
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