3zxa

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Current revision (07:13, 1 May 2024) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3zxa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Turnip_crinkle_virus Turnip crinkle virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZXA FirstGlance]. <br>
<table><tr><td colspan='2'>[[3zxa]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Turnip_crinkle_virus Turnip crinkle virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZXA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZXA FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3zx8|3zx8]], [[3zx9|3zx9]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zxa OCA], [https://pdbe.org/3zxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zxa RCSB], [https://www.ebi.ac.uk/pdbsum/3zxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zxa ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zxa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zxa OCA], [https://pdbe.org/3zxa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zxa RCSB], [https://www.ebi.ac.uk/pdbsum/3zxa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zxa ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/CAPSD_TCV CAPSD_TCV]] Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins. Also acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.<ref>PMID:12477856</ref> <ref>PMID:12620795</ref> <ref>PMID:20439431</ref>
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[https://www.uniprot.org/uniprot/CAPSD_TCV CAPSD_TCV] Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins. Also acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs.<ref>PMID:12477856</ref> <ref>PMID:12620795</ref> <ref>PMID:20439431</ref>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The structure of turnip crinkle virus has been determined at 3.2 A resolution, using the electron density of tomato bushy stunt virus as a starting point for phase refinement by non-crystallographic symmetry. The structures are very closely related, especially in the subunit arm and S domain, where only small insertions and deletions and small co-ordinate shifts relate one chain to another. The P domains, although quite similar in fold, are oriented somewhat differently with respect to the S domains. Understanding of the structure of turnip crinkle virus has been important for analyzing its assembly, as described in an accompanying paper.
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Structure and assembly of turnip crinkle virus. I. X-ray crystallographic structure analysis at 3.2 A resolution.,Hogle JM, Maeda A, Harrison SC J Mol Biol. 1986 Oct 20;191(4):625-38. PMID:3806676<ref>PMID:3806676</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3zxa" style="background-color:#fffaf0;"></div>
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==See Also==
==See Also==
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[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Turnip crinkle virus]]
[[Category: Turnip crinkle virus]]
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[[Category: Harrison, S C]]
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[[Category: Harrison SC]]
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[[Category: Hogle, J M]]
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[[Category: Hogle JM]]
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[[Category: Maeda, A]]
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[[Category: Maeda A]]
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[[Category: Icosahedral virus]]
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[[Category: Ssrna virus]]
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[[Category: Virus]]
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Current revision

Structure and Assembly of Turnip Crinkle Virus I. X-ray Crystallographic Structure Analysis at 3.2 A Resolution

PDB ID 3zxa

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