7a3p
From Proteopedia
(Difference between revisions)
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| - | ==== | + | ==Crystal structure of dengue 3 virus envelope glycoprotein in complex with the scFv fragment of the broadly neutralizing human antibody EDE1 C10== |
| - | <StructureSection load='7a3p' size='340' side='right'caption='[[7a3p]]' scene=''> | + | <StructureSection load='7a3p' size='340' side='right'caption='[[7a3p]], [[Resolution|resolution]] 3.19Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7a3p]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Dengue_virus_3 Dengue virus 3] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7A3P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7A3P FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a3p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a3p OCA], [https://pdbe.org/7a3p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a3p RCSB], [https://www.ebi.ac.uk/pdbsum/7a3p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a3p ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.19Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7a3p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7a3p OCA], [https://pdbe.org/7a3p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7a3p RCSB], [https://www.ebi.ac.uk/pdbsum/7a3p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7a3p ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/O39791_9FLAV O39791_9FLAV] Component of the viral RNA replication complex that functions in virion assembly and antagonizes the host immune response.[ARBA:ARBA00024317] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Monoclonal Antibodies 3D structures|Monoclonal Antibodies 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Dengue virus 3]] | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Duquerroy S]] |
| + | [[Category: Guardado-Calvo P]] | ||
| + | [[Category: Rey FA]] | ||
| + | [[Category: Rouvinski A]] | ||
| + | [[Category: Sharma A]] | ||
| + | [[Category: Vaney MC]] | ||
Current revision
Crystal structure of dengue 3 virus envelope glycoprotein in complex with the scFv fragment of the broadly neutralizing human antibody EDE1 C10
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