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7aia
From Proteopedia
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==Complex of human GDAP1 with hexadecanedioic acid== | ==Complex of human GDAP1 with hexadecanedioic acid== | ||
| - | <StructureSection load='7aia' size='340' side='right'caption='[[7aia]]' scene=''> | + | <StructureSection load='7aia' size='340' side='right'caption='[[7aia]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AIA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AIA FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7aia]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AIA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AIA FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7aia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7aia OCA], [https://pdbe.org/7aia PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7aia RCSB], [https://www.ebi.ac.uk/pdbsum/7aia PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7aia ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EOH:ETHANOL'>EOH</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=RF8:hexadecanedioic+acid'>RF8</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7aia FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7aia OCA], [https://pdbe.org/7aia PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7aia RCSB], [https://www.ebi.ac.uk/pdbsum/7aia PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7aia ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/GDAP1_HUMAN GDAP1_HUMAN] Charcot-Marie-Tooth disease type 2H;Autosomal recessive intermediate Charcot-Marie-Tooth disease type A;Autosomal dominant Charcot-Marie-Tooth disease type 2K;Autosomal recessive Charcot-Marie-Tooth disease with hoarseness;Charcot-Marie-Tooth disease type 4A. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GDAP1_HUMAN GDAP1_HUMAN] Regulates the mitochondrial network by promoting mitochondrial fission.<ref>PMID:16172208</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Kursula P]] | [[Category: Kursula P]] | ||
[[Category: Nguyen GTT]] | [[Category: Nguyen GTT]] | ||
[[Category: Sutinen A]] | [[Category: Sutinen A]] | ||
Revision as of 07:44, 1 May 2024
Complex of human GDAP1 with hexadecanedioic acid
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