7am7

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==Crystal structure of Peptiligase mutant - M222P/L217H/A225N/F189W/N218D==
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<StructureSection load='7am7' size='340' side='right'caption='[[7am7]]' scene=''>
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<StructureSection load='7am7' size='340' side='right'caption='[[7am7]], [[Resolution|resolution]] 2.61&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7am7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_amyloliquefaciens Bacillus amyloliquefaciens] and [https://en.wikipedia.org/wiki/Hirudo_medicinalis Hirudo medicinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7AM7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7AM7 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7am7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7am7 OCA], [https://pdbe.org/7am7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7am7 RCSB], [https://www.ebi.ac.uk/pdbsum/7am7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7am7 ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.61&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7am7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7am7 OCA], [https://pdbe.org/7am7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7am7 RCSB], [https://www.ebi.ac.uk/pdbsum/7am7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7am7 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SUBT_BACAM SUBT_BACAM] Subtilisin is an extracellular alkaline serine protease, it catalyzes the hydrolysis of proteins and peptide amides. Has a high substrate specificity to fibrin.<ref>PMID:12524032</ref>
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus amyloliquefaciens]]
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[[Category: Hirudo medicinalis]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Z-disk]]
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[[Category: Janssen DJ]]
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[[Category: Rozeboom HJ]]

Revision as of 07:45, 1 May 2024

Crystal structure of Peptiligase mutant - M222P/L217H/A225N/F189W/N218D

PDB ID 7am7

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