8pfq
From Proteopedia
(Difference between revisions)
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pfq OCA], [https://pdbe.org/8pfq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pfq RCSB], [https://www.ebi.ac.uk/pdbsum/8pfq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pfq ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8pfq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8pfq OCA], [https://pdbe.org/8pfq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8pfq RCSB], [https://www.ebi.ac.uk/pdbsum/8pfq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8pfq ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | All widely used mRNA vaccines against COVID-19 contain in their sequence 1-methylpseudouridine (m1Psi) instead of uridine. In this publication, we report two high resolution crystal structures (at up to 1.01 and 1.32 A respectively) of one such double-stranded 12-mer RNA sequence crystallized in two crystal forms. The structures are compared with similar structures which do not contain this modification. Additionally, the structure of 1-methyl-pseudouridine itself was determined. | ||
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| - | RNA oligomers at atomic resolution containing 1-methylpseudouridine, an essential building block of mRNA vaccines.,Nievergelt P, Berliat F, McAuley K, Dorgan CR, van Well RM, Thorn A, Spingler B ChemMedChem. 2024 Jan 18:e202300600. doi: 10.1002/cmdc.202300600. PMID:38235959<ref>PMID:38235959</ref> | ||
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 8pfq" style="background-color:#fffaf0;"></div> | ||
| - | == References == | ||
| - | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 08:02, 1 May 2024
RNA structure with 1-methylpseudoridine, P1 space group
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