1rw1

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[[Image:1rw1.gif|left|200px]]
[[Image:1rw1.gif|left|200px]]
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{{Structure
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|PDB= 1rw1 |SIZE=350|CAPTION= <scene name='initialview01'>1rw1</scene>, resolution 1.02&Aring;
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The line below this paragraph, containing "STRUCTURE_1rw1", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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|GENE= yffB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=208964 Pseudomonas aeruginosa PAO1])
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{{STRUCTURE_1rw1| PDB=1rw1 | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rw1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rw1 OCA], [http://www.ebi.ac.uk/pdbsum/1rw1 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1rw1 RCSB]</span>
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'''YFFB (PA3664) PROTEIN'''
'''YFFB (PA3664) PROTEIN'''
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[[Category: S2F, Structure 2.Function Project.]]
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[[Category: Teplyakov, A.]]
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[[Category: structural genomic]]
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[[Category: Structure 2 function project]]
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[[Category: thioredoxin fold]]
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Revision as of 04:58, 3 May 2008

Template:STRUCTURE 1rw1

YFFB (PA3664) PROTEIN


Overview

BACKGROUND: The yffB (PA3664) gene of Pseudomonas aeruginosa encodes an uncharacterized protein of 13 kDa molecular weight with a marginal sequence similarity to arsenate reductase from Escherichia coli. The crystal structure determination of YffB was undertaken as part of a structural genomics effort in order to assist with the functional assignment of the protein. RESULTS: The structure was determined at 1.0 A resolution by single-wavelength anomalous diffraction. The fold is very similar to that of arsenate reductase, which is an extension of the thioredoxin fold. CONCLUSION: Given the conservation of the functionally important residues and the ability to bind glutathione, YffB is likely to function as a GSH-dependent thiol reductase.

About this Structure

1RW1 is a Single protein structure of sequence from Pseudomonas aeruginosa pao1. Full crystallographic information is available from OCA.

Reference

Crystal structure of the YffB protein from Pseudomonas aeruginosa suggests a glutathione-dependent thiol reductase function., Teplyakov A, Pullalarevu S, Obmolova G, Doseeva V, Galkin A, Herzberg O, Dauter M, Dauter Z, Gilliland GL, BMC Struct Biol. 2004 Mar 8;4:5. PMID:15102337 Page seeded by OCA on Sat May 3 07:58:22 2008

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