1sg7
From Proteopedia
(Difference between revisions)
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==NMR solution structure of the putative cation transport regulator ChaB== | ==NMR solution structure of the putative cation transport regulator ChaB== | ||
| - | <StructureSection load='1sg7' size='340' side='right'caption='[[1sg7 | + | <StructureSection load='1sg7' size='340' side='right'caption='[[1sg7]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1sg7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1sg7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SG7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SG7 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sg7 OCA], [https://pdbe.org/1sg7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sg7 RCSB], [https://www.ebi.ac.uk/pdbsum/1sg7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sg7 ProSAT], [https://www.topsan.org/Proteins/BSGI/1sg7 TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sg7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sg7 OCA], [https://pdbe.org/1sg7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sg7 RCSB], [https://www.ebi.ac.uk/pdbsum/1sg7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sg7 ProSAT], [https://www.topsan.org/Proteins/BSGI/1sg7 TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CHAB_ECO57 CHAB_ECO57] Might be a regulator of the sodium-potassium/proton antiporter ChaA.<ref>PMID:15306028</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sg7 ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sg7 ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| - | <div style="background-color:#fffaf0;"> | ||
| - | == Publication Abstract from PubMed == | ||
| - | BACKGROUND: ChaB is a putative regulator of ChaA, a Na+/H+ antiporter that also has Ca+/H+ activity in E. coli. ChaB contains a conserved 60-residue region of unknown function found in other bacteria, archaeabacteria and a series of baculoviral proteins. As part of a structural genomics project, the structure of ChaB was elucidated by NMR spectroscopy. RESULTS: The structure of ChaB is composed of 3 alpha-helices and a small sheet that pack tightly to form a fold that is found in the cyclin-box family of proteins. CONCLUSION: ChaB is distinguished from its putative DNA binding sequence homologues by a highly charged flexible loop region that has weak affinity to Mg2+ and Ca2+ divalent metal ions. | ||
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| - | The solution structure of ChaB, a putative membrane ion antiporter regulator from Escherichia coli.,Osborne MJ, Siddiqui N, Iannuzzi P, Gehring K BMC Struct Biol. 2004 Aug 11;4:9. PMID:15306028<ref>PMID:15306028</ref> | ||
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| - | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
| - | </div> | ||
| - | <div class="pdbe-citations 1sg7" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Escherichia coli]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Cygler M]] | |
| - | [[Category: Cygler | + | [[Category: Gehring K]] |
| - | [[Category: Gehring | + | [[Category: Osborne MJ]] |
| - | [[Category: Osborne | + | [[Category: Siddiqui N]] |
| - | [[Category: Siddiqui | + | |
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Revision as of 08:31, 1 May 2024
NMR solution structure of the putative cation transport regulator ChaB
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