8q3r
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of the DNA polymerase holoenzyme E9-A20-D4 of vaccinia virus== | |
| - | + | <StructureSection load='8q3r' size='340' side='right'caption='[[8q3r]], [[Resolution|resolution]] 3.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8q3r]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus_Copenhagen Vaccinia virus Copenhagen]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Q3R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Q3R FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.8Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8q3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8q3r OCA], [https://pdbe.org/8q3r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8q3r RCSB], [https://www.ebi.ac.uk/pdbsum/8q3r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8q3r ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/UNG_VACCC UNG_VACCC] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Vaccinia virus Copenhagen]] | ||
| + | [[Category: Ballandras-Colas A]] | ||
| + | [[Category: Boettcher B]] | ||
| + | [[Category: Burmeister WP]] | ||
| + | [[Category: Grimm C]] | ||
Revision as of 08:33, 9 May 2024
Cryo-EM structure of the DNA polymerase holoenzyme E9-A20-D4 of vaccinia virus
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