8qam
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==vaccinia virus Uracil DNA glycosidase mutant I197K-V200E-L204K== | |
| - | + | <StructureSection load='8qam' size='340' side='right'caption='[[8qam]], [[Resolution|resolution]] 1.32Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8qam]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus_Copenhagen Vaccinia virus Copenhagen]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QAM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QAM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.32Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qam FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qam OCA], [https://pdbe.org/8qam PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qam RCSB], [https://www.ebi.ac.uk/pdbsum/8qam PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qam ProSAT]</span></td></tr> |
| - | [[Category: Burmeister | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/UNG_VACCC UNG_VACCC] Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. Also part of a heterodimeric processivity factor which potentiates the DNA polymerase activity. Binds to DNA (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Vaccinia virus Copenhagen]] | ||
| + | [[Category: Burmeister WP]] | ||
| + | [[Category: Tarbouriech N]] | ||
Revision as of 08:33, 9 May 2024
vaccinia virus Uracil DNA glycosidase mutant I197K-V200E-L204K
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