1nxi

From Proteopedia

(Difference between revisions)

Current revision

Solution structure of Vibrio cholerae protein VC0424

Structural highlights

1nxi is a 1 chain structure with sequence from Vibrio cholerae. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Solution NMR
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT, TOPSAN

Function

Q9KUU1_VIBCH Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (By similarity).[HAMAP-Rule:MF_01888]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

Publication Abstract from PubMed

The structure of Vibrio cholerae protein VC0424 was determined by NMR spectroscopy. VC0424 belongs to a conserved family of bacterial proteins of unknown function (COG 3076). The structure has an alpha-beta sandwich architecture consisting of two layers: a four-stranded antiparallel beta-sheet and three side-by-side alpha-helices. The secondary structure elements have the order alphabetaalphabetabetaalphabeta along the sequence. This fold is the same as the ferredoxin-like fold, except with an additional long N-terminal helix, making it a variation on this common motif. A cluster of conserved surface residues on the beta-sheet side of the protein forms a pocket that may be important for the biological function of this conserved family of proteins.

Solution structure of Vibrio cholerae protein VC0424: a variation of the ferredoxin-like fold.,Ramelot TA, Ni S, Goldsmith-Fischman S, Cort JR, Honig B, Kennedy MA Protein Sci. 2003 Jul;12(7):1556-61. PMID:12824501^[1]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

References

↑ Ramelot TA, Ni S, Goldsmith-Fischman S, Cort JR, Honig B, Kennedy MA. Solution structure of Vibrio cholerae protein VC0424: a variation of the ferredoxin-like fold. Protein Sci. 2003 Jul;12(7):1556-61. PMID:12824501

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 Publication Abstract from PubMed
5 References

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1nxi"

@@ Line 4: / Line 4: @@
 == Structural highlights ==
 <table><tr><td colspan='2'>[[1nxi]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae Vibrio cholerae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NXI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NXI FirstGlance]. <br>
-</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nxi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nxi OCA], [https://pdbe.org/1nxi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nxi RCSB], [https://www.ebi.ac.uk/pdbsum/1nxi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nxi ProSAT], [https://www.topsan.org/Proteins/NESGC/1nxi TOPSAN]</span></td></tr>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nxi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nxi OCA], [https://pdbe.org/1nxi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nxi RCSB], [https://www.ebi.ac.uk/pdbsum/1nxi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nxi ProSAT], [https://www.topsan.org/Proteins/NESGC/1nxi TOPSAN]</span></td></tr>
 </table>
 == Function ==

1nxi

From Proteopedia

Current revision

Solution structure of Vibrio cholerae protein VC0424

Structural highlights

Function

Evolutionary Conservation

Publication Abstract from PubMed

References

Contents

Proteopedia Page Contributors and Editors (what is this?)

Views

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