2bj8

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Current revision (09:16, 9 May 2024) (edit) (undo)
 
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<StructureSection load='2bj8' size='340' side='right'caption='[[2bj8]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='2bj8' size='340' side='right'caption='[[2bj8]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2bj8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BJ8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2bj8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii_OT3 Pyrococcus horikoshii OT3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BJ8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BJ8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2bj1|2bj1]], [[2bj3|2bj3]], [[2bj7|2bj7]], [[2bj9|2bj9]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bj8 OCA], [https://pdbe.org/2bj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bj8 RCSB], [https://www.ebi.ac.uk/pdbsum/2bj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bj8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2bj8 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bj8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bj8 OCA], [https://pdbe.org/2bj8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bj8 RCSB], [https://www.ebi.ac.uk/pdbsum/2bj8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bj8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2bj8 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/NIKR_PYRHO NIKR_PYRHO]] Transcriptional regulator (Potential).
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[https://www.uniprot.org/uniprot/NIKR_PYRHO NIKR_PYRHO] Transcriptional regulator (Potential).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pyrococcus horikoshii]]
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[[Category: Pyrococcus horikoshii OT3]]
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[[Category: Tahirov, T H]]
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[[Category: Tahirov TH]]
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[[Category: Dna-binding]]
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[[Category: Metal-binding]]
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[[Category: Nickel]]
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[[Category: Nikr]]
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[[Category: Repressor]]
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[[Category: Structural genomic]]
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[[Category: Rsgi]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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Current revision

NIKR IN CLOSED CONFORMATION AND NICKEL BOUND TO HIGH and LOW-AFFINITY SITES

PDB ID 2bj8

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OCA

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