2j7j

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Current revision (09:35, 9 May 2024) (edit) (undo)
 
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<StructureSection load='2j7j' size='340' side='right'caption='[[2j7j]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='2j7j' size='340' side='right'caption='[[2j7j]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2j7j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/African_clawed_frog African clawed frog]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J7J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J7J FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2j7j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J7J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J7J FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1tf3|1tf3]], [[1tf6|1tf6]], [[1un6|1un6]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j7j OCA], [https://pdbe.org/2j7j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j7j RCSB], [https://www.ebi.ac.uk/pdbsum/2j7j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j7j ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j7j OCA], [https://pdbe.org/2j7j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j7j RCSB], [https://www.ebi.ac.uk/pdbsum/2j7j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j7j ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TF3A_XENLA TF3A_XENLA] Acts as both a positive transcription factor for 5S RNA genes and a specific RNA binding protein that complexes with 5S RNA in oocytes to form the 7S ribonucleoprotein storage particle. May play an essential role in the developmental change in 5S RNA gene expression. Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: African clawed frog]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Klug, A]]
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[[Category: Xenopus laevis]]
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[[Category: Lu, D]]
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[[Category: Klug A]]
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[[Category: Alternative initiation]]
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[[Category: Lu D]]
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[[Category: Dna-binding]]
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[[Category: Hydrophobic core]]
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[[Category: Metal-binding]]
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[[Category: Nuclear protein]]
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[[Category: Phosphorylation]]
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[[Category: Polymorphism]]
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[[Category: Rna-binding]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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[[Category: Zinc]]
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[[Category: Zinc finger module]]
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[[Category: Zinc-finger]]
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Current revision

Invariance of the zinc finger module: a comparison of the free structure with those in nucleic-acid complexes

PDB ID 2j7j

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