2j7j
From Proteopedia
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<StructureSection load='2j7j' size='340' side='right'caption='[[2j7j]], [[Resolution|resolution]] 1.65Å' scene=''> | <StructureSection load='2j7j' size='340' side='right'caption='[[2j7j]], [[Resolution|resolution]] 1.65Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[2j7j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2j7j]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J7J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J7J FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> |
- | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j7j OCA], [https://pdbe.org/2j7j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j7j RCSB], [https://www.ebi.ac.uk/pdbsum/2j7j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j7j ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j7j OCA], [https://pdbe.org/2j7j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j7j RCSB], [https://www.ebi.ac.uk/pdbsum/2j7j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j7j ProSAT]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/TF3A_XENLA TF3A_XENLA] Acts as both a positive transcription factor for 5S RNA genes and a specific RNA binding protein that complexes with 5S RNA in oocytes to form the 7S ribonucleoprotein storage particle. May play an essential role in the developmental change in 5S RNA gene expression. Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's. | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: African clawed frog]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: | + | [[Category: Xenopus laevis]] |
- | [[Category: | + | [[Category: Klug A]] |
- | [[Category: | + | [[Category: Lu D]] |
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Current revision
Invariance of the zinc finger module: a comparison of the free structure with those in nucleic-acid complexes
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