2jle

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Current revision (09:38, 9 May 2024) (edit) (undo)
 
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<StructureSection load='2jle' size='340' side='right'caption='[[2jle]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
<StructureSection load='2jle' size='340' side='right'caption='[[2jle]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2jle]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/9hiv1 9hiv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JLE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JLE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2jle]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JLE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JLE FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=I15:5-[(5-FLUORO-3-METHYL-1H-INDAZOL-4-YL)OXY]BENZENE-1,3-DICARBONITRILE'>I15</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=I15:5-[(5-FLUORO-3-METHYL-1H-INDAZOL-4-YL)OXY]BENZENE-1,3-DICARBONITRILE'>I15</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jle FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jle OCA], [https://pdbe.org/2jle PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jle RCSB], [https://www.ebi.ac.uk/pdbsum/2jle PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jle ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jle FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jle OCA], [https://pdbe.org/2jle PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jle RCSB], [https://www.ebi.ac.uk/pdbsum/2jle PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jle ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q72547_9HIV1 Q72547_9HIV1]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human immunodeficiency virus 1]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Allan, G]]
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[[Category: Allan G]]
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[[Category: Barba, O]]
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[[Category: Barba O]]
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[[Category: Burt, C]]
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[[Category: Burt C]]
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[[Category: Corbau, R]]
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[[Category: Corbau R]]
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[[Category: Dupont, T]]
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[[Category: Dupont T]]
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[[Category: Irving, S]]
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[[Category: Irving S]]
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[[Category: Jones, L H]]
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[[Category: Jones LH]]
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[[Category: Mowbray, C E]]
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[[Category: Mowbray CE]]
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[[Category: Phillips, C]]
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[[Category: Phillips C]]
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[[Category: Swain, N A]]
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[[Category: Swain NA]]
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[[Category: Webster, R]]
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[[Category: Webster R]]
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[[Category: Westby, M]]
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[[Category: Westby M]]
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[[Category: Aid]]
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[[Category: Aspartyl protease]]
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[[Category: Capsid maturation]]
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[[Category: Capsid protein]]
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[[Category: Cytoplasm]]
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[[Category: Dna integration]]
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[[Category: Dna recombination]]
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[[Category: Dna-directed dna polymerase]]
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[[Category: Endonuclease]]
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[[Category: Hiv-1]]
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[[Category: Hydrolase]]
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[[Category: Lipoprotein]]
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[[Category: Magnesium]]
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[[Category: Metal-binding]]
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[[Category: Multifunctional enzyme]]
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[[Category: Myristate]]
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[[Category: Nnrti]]
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[[Category: Nuclease]]
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[[Category: Nucleotidyltransferase]]
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[[Category: Nucleus]]
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[[Category: Phosphoprotein]]
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[[Category: Protease]]
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[[Category: Ribosomal frameshifting]]
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[[Category: Rna-binding]]
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[[Category: Rna-directed dna polymerase]]
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[[Category: Transferase]]
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[[Category: Viral nucleoprotein]]
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[[Category: Virion]]
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[[Category: Zinc]]
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[[Category: Zinc-finger]]
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Current revision

Novel indazole nnrtis created using molecular template hybridization based on crystallographic overlays

PDB ID 2jle

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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