4ckh

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ckh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CKH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CKH FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ckh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CKH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CKH FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ckh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ckh OCA], [https://pdbe.org/4ckh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ckh RCSB], [https://www.ebi.ac.uk/pdbsum/4ckh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ckh ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 14&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ckh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ckh OCA], [https://pdbe.org/4ckh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ckh RCSB], [https://www.ebi.ac.uk/pdbsum/4ckh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ckh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ACAP1_HUMAN ACAP1_HUMAN]] GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.<ref>PMID:11062263</ref> <ref>PMID:16256741</ref> <ref>PMID:17398097</ref> <ref>PMID:17664335</ref> <ref>PMID:22645133</ref>
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[https://www.uniprot.org/uniprot/ACAP1_HUMAN ACAP1_HUMAN] GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.<ref>PMID:11062263</ref> <ref>PMID:16256741</ref> <ref>PMID:17398097</ref> <ref>PMID:17664335</ref> <ref>PMID:22645133</ref>
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==

Current revision

Helical reconstruction of ACAP1(BAR-PH domain) decorated membrane tubules by cryo-electron microscopy

4ckh, resolution 14.00Å

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OCA

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