4d5c

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Current revision (11:17, 9 May 2024) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4d5c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Proteus_mirabilis Proteus mirabilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D5C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D5C FirstGlance]. <br>
<table><tr><td colspan='2'>[[4d5c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Proteus_mirabilis Proteus mirabilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4D5C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4D5C FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d5c OCA], [https://pdbe.org/4d5c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d5c RCSB], [https://www.ebi.ac.uk/pdbsum/4d5c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d5c ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4d5c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4d5c OCA], [https://pdbe.org/4d5c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4d5c RCSB], [https://www.ebi.ac.uk/pdbsum/4d5c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4d5c ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/Q9ZI84_PROMI Q9ZI84_PROMI]] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.[ARBA:ARBA00002856]
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[https://www.uniprot.org/uniprot/Q9ZI84_PROMI Q9ZI84_PROMI] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites.[ARBA:ARBA00002856]
==See Also==
==See Also==

Current revision

tetracycline repressor class J, apo form

PDB ID 4d5c

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