9eoq
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM Structure of a 1033 Scaffold Base DNA Origami Nanostructure V4 and TBA== | |
| + | <StructureSection load='9eoq' size='340' side='right'caption='[[9eoq]], [[Resolution|resolution]] 7.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[9eoq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9EOQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9EOQ FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 7.5Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9eoq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9eoq OCA], [https://pdbe.org/9eoq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9eoq RCSB], [https://www.ebi.ac.uk/pdbsum/9eoq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9eoq ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | DNA origami, a method for constructing nanostructures from DNA, offers potential for diverse scientific and technological applications due to its ability to integrate various molecular functionalities in a programmable manner. In this study, we examined the impact of internal crossover distribution and the compositional uniformity of staple strands on the structure of multilayer DNA origami using cryogenic electron microscopy (cryo-EM) single-particle analysis. A refined DNA object was utilized as an alignment framework in a host-guest model, where we successfully resolved an 8 kDa thrombin binding aptamer (TBA) linked to the host object. Our results broaden the spectrum of DNA in structural applications. | ||
| - | + | Designing Rigid DNA Origami Templates for Molecular Visualization Using Cryo-EM.,Khoshouei A, Kempf G, Mykhailiuk V, Griessing JM, Honemann MN, Kater L, Cavadini S, Dietz H Nano Lett. 2024 Apr 11;24(16):5031-8. doi: 10.1021/acs.nanolett.4c00915. PMID:38602296<ref>PMID:38602296</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| + | <div class="pdbe-citations 9eoq" style="background-color:#fffaf0;"></div> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Ali K]] | ||
| + | [[Category: Georg K]] | ||
| + | [[Category: Hendrik D]] | ||
| + | [[Category: Johanna G]] | ||
| + | [[Category: Lukas K]] | ||
| + | [[Category: Maximilian NH]] | ||
| + | [[Category: Simone C]] | ||
| + | [[Category: Volodymyr M]] | ||
Current revision
Cryo-EM Structure of a 1033 Scaffold Base DNA Origami Nanostructure V4 and TBA
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Categories: Large Structures | Synthetic construct | Ali K | Georg K | Hendrik D | Johanna G | Lukas K | Maximilian NH | Simone C | Volodymyr M
