1uzc

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Current revision (13:23, 9 May 2024) (edit) (undo)
 
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==THE STRUCTURE OF AN FF DOMAIN FROM HUMAN HYPA/FBP11==
==THE STRUCTURE OF AN FF DOMAIN FROM HUMAN HYPA/FBP11==
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<StructureSection load='1uzc' size='340' side='right'caption='[[1uzc]], [[NMR_Ensembles_of_Models | 23 NMR models]]' scene=''>
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<StructureSection load='1uzc' size='340' side='right'caption='[[1uzc]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1uzc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1h40 1h40]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UZC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UZC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1uzc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1h40 1h40]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UZC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UZC FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uzc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uzc OCA], [https://pdbe.org/1uzc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uzc RCSB], [https://www.ebi.ac.uk/pdbsum/1uzc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uzc ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uzc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uzc OCA], [https://pdbe.org/1uzc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uzc RCSB], [https://www.ebi.ac.uk/pdbsum/1uzc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uzc ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PR40A_HUMAN PR40A_HUMAN] Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function (By similarity). Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing.<ref>PMID:21834987</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Allen, M D]]
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[[Category: Allen MD]]
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[[Category: Bycroft, M]]
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[[Category: Bycroft M]]
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[[Category: Friedler, A]]
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[[Category: Friedler A]]
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[[Category: Jemth, P]]
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[[Category: Jemth P]]
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[[Category: Schon, O]]
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[[Category: Schon O]]
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[[Category: Nuclear protein]]
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[[Category: Phosphopeptide recognition]]
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[[Category: Rna polymerase ii carboxyl-terminal domain]]
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[[Category: Transcription]]
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Current revision

THE STRUCTURE OF AN FF DOMAIN FROM HUMAN HYPA/FBP11

PDB ID 1uzc

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