1wfk
From Proteopedia
(Difference between revisions)
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==FYVE domain of FYVE domain containing 19 protein from Mus musculus== | ==FYVE domain of FYVE domain containing 19 protein from Mus musculus== | ||
| - | <StructureSection load='1wfk' size='340' side='right'caption='[[1wfk | + | <StructureSection load='1wfk' size='340' side='right'caption='[[1wfk]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1wfk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1wfk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WFK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WFK FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wfk OCA], [https://pdbe.org/1wfk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wfk RCSB], [https://www.ebi.ac.uk/pdbsum/1wfk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wfk ProSAT], [https://www.topsan.org/Proteins/RSGI/1wfk TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wfk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wfk OCA], [https://pdbe.org/1wfk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wfk RCSB], [https://www.ebi.ac.uk/pdbsum/1wfk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wfk ProSAT], [https://www.topsan.org/Proteins/RSGI/1wfk TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/ANCHR_MOUSE ANCHR_MOUSE] Key regulator of abscission step in cytokinesis: part of the cytokinesis checkpoint, a process required to delay abscission to prevent both premature resolution of intercellular chromosome bridges and accumulation of DNA damage. Together with CHMP4C, required to retain abscission-competent VPS4 (VPS4A and/or VPS4B) at the midbody ring until abscission checkpoint signaling is terminated at late cytokinesis. Deactivation of AURKB results in dephosphorylation of CHMP4C followed by its dissociation from ZFYVE19/ANCHR and VPS4 and subsequent abscission (By similarity). | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Mus musculus]] |
| - | [[Category: Hayashi | + | [[Category: Hayashi F]] |
| - | [[Category: Nagashima | + | [[Category: Nagashima T]] |
| - | + | [[Category: Yokoyama S]] | |
| - | [[Category: Yokoyama | + | |
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Current revision
FYVE domain of FYVE domain containing 19 protein from Mus musculus
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