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1wta
From Proteopedia
(Difference between revisions)
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<StructureSection load='1wta' size='340' side='right'caption='[[1wta]], [[Resolution|resolution]] 1.78Å' scene=''> | <StructureSection load='1wta' size='340' side='right'caption='[[1wta]], [[Resolution|resolution]] 1.78Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1wta]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1wta]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aeropyrum_pernix_K1 Aeropyrum pernix K1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WTA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WTA FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.78Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADE:ADENINE'>ADE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wta OCA], [https://pdbe.org/1wta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wta RCSB], [https://www.ebi.ac.uk/pdbsum/1wta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wta ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wta FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wta OCA], [https://pdbe.org/1wta PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wta RCSB], [https://www.ebi.ac.uk/pdbsum/1wta PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wta ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MTAP_AERPE MTAP_AERPE] Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.[HAMAP-Rule:MF_01963] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Aeropyrum pernix K1]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | + | [[Category: Murakami Y]] | |
| - | [[Category: Murakami | + | [[Category: Nakamura KT]] |
| - | [[Category: Nakamura | + | [[Category: Tsunoda M]] |
| - | [[Category: Tsunoda | + | |
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of 5'-Deoxy-5'-methylthioadenosine from Aeropyrum pernix (R32 form)
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