8oxr

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (05:20, 15 May 2024) (edit) (undo)
 
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 8oxr is ON HOLD until Paper Publication
+
==Structure of the N-terminal didomain d1_d2 of the Thrombospondin type-1 domain-containing 7A==
-
 
+
<StructureSection load='8oxr' size='340' side='right'caption='[[8oxr]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-
Authors: Bochel, A., Mortensen, S.A., Chojnowski, G., Wilmanns, M.
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[8oxr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8OXR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8OXR FirstGlance]. <br>
-
Description: Structure of the N-terminal didomain d1_d2 of the Thrombospondin type-1 domain-containing 7A
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-
[[Category: Unreleased Structures]]
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8oxr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8oxr OCA], [https://pdbe.org/8oxr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8oxr RCSB], [https://www.ebi.ac.uk/pdbsum/8oxr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8oxr ProSAT]</span></td></tr>
-
[[Category: Wilmanns, M]]
+
</table>
-
[[Category: Mortensen, S.A]]
+
== Disease ==
-
[[Category: Chojnowski, G]]
+
[https://www.uniprot.org/uniprot/THS7A_HUMAN THS7A_HUMAN] Autoantibodies against THSD7A have been detected in serum and glomeruli from patients with idiopathic membranous nephropathy (PubMed:25394321). The majority of the autoantibodies react with the two most N-terminal TSP type-1 domains (PubMed:29555830).<ref>PMID:25394321</ref> <ref>PMID:29555830</ref>
-
[[Category: Bochel, A]]
+
== Function ==
 +
[https://www.uniprot.org/uniprot/THS7A_HUMAN THS7A_HUMAN] Plays a role in actin cytoskeleton rearrangement.<ref>PMID:27214550</ref> The soluble form promotes endothelial cell migration and filopodia formation during sprouting angiogenesis via a FAK-dependent mechanism.<ref>PMID:22194972</ref>
 +
== References ==
 +
<references/>
 +
__TOC__
 +
</StructureSection>
 +
[[Category: Homo sapiens]]
 +
[[Category: Large Structures]]
 +
[[Category: Bochel A]]
 +
[[Category: Chojnowski G]]
 +
[[Category: Mortensen SA]]
 +
[[Category: Wilmanns M]]

Current revision

Structure of the N-terminal didomain d1_d2 of the Thrombospondin type-1 domain-containing 7A

PDB ID 8oxr

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/8oxr"
Personal tools