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2a3s

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Current revision (08:15, 15 May 2024) (edit) (undo)
 
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==Solution structure and Dynamics of DNA-Binding Domain of Myocyte Nuclear Factor==
==Solution structure and Dynamics of DNA-Binding Domain of Myocyte Nuclear Factor==
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<StructureSection load='2a3s' size='340' side='right'caption='[[2a3s]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2a3s' size='340' side='right'caption='[[2a3s]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2a3s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A3S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A3S FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2a3s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A3S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A3S FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Foxk1(AMINO ACID 287-387) ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a3s OCA], [https://pdbe.org/2a3s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a3s RCSB], [https://www.ebi.ac.uk/pdbsum/2a3s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a3s ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a3s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a3s OCA], [https://pdbe.org/2a3s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2a3s RCSB], [https://www.ebi.ac.uk/pdbsum/2a3s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a3s ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/FOXK1_MOUSE FOXK1_MOUSE]] Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. Has a role in myogenic differentiation and in remodeling processes of adult muscles that occur in response to physiological stimuli.<ref>PMID:8007964</ref> <ref>PMID:9271401</ref>
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[https://www.uniprot.org/uniprot/FOXK1_MOUSE FOXK1_MOUSE] Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene. Has a role in myogenic differentiation and in remodeling processes of adult muscles that occur in response to physiological stimuli.<ref>PMID:8007964</ref> <ref>PMID:9271401</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Chang, C H]]
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[[Category: Chang C-H]]
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[[Category: Chu, Y P]]
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[[Category: Chu Y-P]]
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[[Category: Chuang, W J]]
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[[Category: Chuang W-J]]
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[[Category: Jeng, W Y]]
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[[Category: Jeng W-Y]]
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[[Category: Dna binding protein]]
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[[Category: Dna-binding domain]]
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[[Category: Forkhead]]
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[[Category: Winged-helix]]
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Solution structure and Dynamics of DNA-Binding Domain of Myocyte Nuclear Factor

PDB ID 2a3s

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