8uo9
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of synaptic vesicle protein 2A in complex with a nanobody== | |
| - | + | <StructureSection load='8uo9' size='340' side='right'caption='[[8uo9]], [[Resolution|resolution]] 3.30Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8uo9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8UO9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8UO9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.3Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PS1:1,2-DIDECANOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE]'>PS1</scene>, <scene name='pdbligand=X49:(4R)-1-{[(4S)-2-(methoxymethyl)-6-(trifluoromethyl)imidazo[2,1-b][1,3,4]thiadiazol-5-yl]methyl}-4-(4,4,4-trifluorobutyl)pyrrolidin-2-one'>X49</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8uo9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8uo9 OCA], [https://pdbe.org/8uo9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8uo9 RCSB], [https://www.ebi.ac.uk/pdbsum/8uo9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8uo9 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SV2A_HUMAN SV2A_HUMAN] Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Lama glama]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Adams C]] | ||
| + | [[Category: Coleman JA]] | ||
| + | [[Category: Horyani PS]] | ||
| + | [[Category: Ledecq M]] | ||
| + | [[Category: Levin E]] | ||
| + | [[Category: Martin MF]] | ||
| + | [[Category: Mittal A]] | ||
| + | [[Category: Yang M]] | ||
Revision as of 08:06, 22 May 2024
Structure of synaptic vesicle protein 2A in complex with a nanobody
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Categories: Homo sapiens | Lama glama | Large Structures | Adams C | Coleman JA | Horyani PS | Ledecq M | Levin E | Martin MF | Mittal A | Yang M
