1s9b

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[[Image:1s9b.gif|left|200px]]
[[Image:1s9b.gif|left|200px]]
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{{Structure
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|PDB= 1s9b |SIZE=350|CAPTION= <scene name='initialview01'>1s9b</scene>, resolution 2.81&Aring;
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The line below this paragraph, containing "STRUCTURE_1s9b", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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or leave the SCENE parameter empty for the default display.
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|GENE=
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|DOMAIN=
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{{STRUCTURE_1s9b| PDB=1s9b | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1s9b FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s9b OCA], [http://www.ebi.ac.uk/pdbsum/1s9b PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1s9b RCSB]</span>
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}}
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'''Crystal Structure Analysis of the B-DNA GAATTCG'''
'''Crystal Structure Analysis of the B-DNA GAATTCG'''
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==About this Structure==
==About this Structure==
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1S9B is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S9B OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S9B OCA].
==Reference==
==Reference==
A cubic arrangement of DNA double helices based on nickel-guanine interactions., Valls N, Uson I, Gouyette C, Subirana JA, J Am Chem Soc. 2004 Jun 30;126(25):7812-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15212528 15212528]
A cubic arrangement of DNA double helices based on nickel-guanine interactions., Valls N, Uson I, Gouyette C, Subirana JA, J Am Chem Soc. 2004 Jun 30;126(25):7812-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15212528 15212528]
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[[Category: Protein complex]]
 
[[Category: Gouyette, C.]]
[[Category: Gouyette, C.]]
[[Category: Subirana, J A.]]
[[Category: Subirana, J A.]]
[[Category: Uson, I.]]
[[Category: Uson, I.]]
[[Category: Valls, N.]]
[[Category: Valls, N.]]
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[[Category: cubic dna]]
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[[Category: Cubic dna]]
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[[Category: double helix]]
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[[Category: Double helix]]
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[[Category: nickel]]
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[[Category: Nickel]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 08:26:36 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 23:39:01 2008''
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Revision as of 05:26, 3 May 2008

Image:1s9b.gif

Template:STRUCTURE 1s9b

Crystal Structure Analysis of the B-DNA GAATTCG


Overview

DNA oligonucleotides can be used in order to assemble highly structured materials. Oligonucleotides with sticky ends can form long linear structures, whereas branching is required to form two- and three-dimensional nanostructures. In this paper, we show that when Ni(2+) is attached to the N7 atom of guanine, it can also act as a branching point. Thus, we have found that the heptanucleotide d(GAATTCG) can assemble into long linear duplex structures, which cross in space to generate a cubic structure. The three-dimensional arrays are stabilized by phosphate-Ni(2+)-guanine interactions. For the first time, the crystallization of a B form DNA oligonucleotide in a cubic system is reported, space group I23. Large solvent cavities are found among the DNA duplexes.

About this Structure

Full crystallographic information is available from OCA.

Reference

A cubic arrangement of DNA double helices based on nickel-guanine interactions., Valls N, Uson I, Gouyette C, Subirana JA, J Am Chem Soc. 2004 Jun 30;126(25):7812-6. PMID:15212528 Page seeded by OCA on Sat May 3 08:26:36 2008

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