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7qe7
From Proteopedia
(Difference between revisions)
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| - | ==== | + | ==High-resolution structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1== |
| - | <StructureSection load='7qe7' size='340' side='right'caption='[[7qe7]]' scene=''> | + | <StructureSection load='7qe7' size='340' side='right'caption='[[7qe7]], [[Resolution|resolution]] 2.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7qe7]] is a 13 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QE7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QE7 FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qe7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qe7 OCA], [https://pdbe.org/7qe7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qe7 RCSB], [https://www.ebi.ac.uk/pdbsum/7qe7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qe7 ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qe7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qe7 OCA], [https://pdbe.org/7qe7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qe7 RCSB], [https://www.ebi.ac.uk/pdbsum/7qe7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qe7 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/APC10_HUMAN APC10_HUMAN] Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.<ref>PMID:18485873</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Z | + | [[Category: Barford D]] |
| + | [[Category: Boland A]] | ||
| + | [[Category: Chang L]] | ||
| + | [[Category: Hoefler A]] | ||
| + | [[Category: Yang J]] | ||
| + | [[Category: Yu J]] | ||
| + | [[Category: Zhang Z]] | ||
Current revision
High-resolution structure of the Anaphase-promoting complex/cyclosome (APC/C) bound to co-activator Cdh1
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Categories: Homo sapiens | Large Structures | Barford D | Boland A | Chang L | Hoefler A | Yang J | Yu J | Zhang Z
