2cqh

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Current revision (11:29, 22 May 2024) (edit) (undo)
 
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==Solution structure of the RNA binding domain of IGF-II mRNA-binding protein 2==
==Solution structure of the RNA binding domain of IGF-II mRNA-binding protein 2==
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<StructureSection load='2cqh' size='340' side='right'caption='[[2cqh]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2cqh' size='340' side='right'caption='[[2cqh]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2cqh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CQH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CQH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2cqh]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CQH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CQH FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Imp2 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cqh OCA], [https://pdbe.org/2cqh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cqh RCSB], [https://www.ebi.ac.uk/pdbsum/2cqh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cqh ProSAT], [https://www.topsan.org/Proteins/RSGI/2cqh TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cqh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cqh OCA], [https://pdbe.org/2cqh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cqh RCSB], [https://www.ebi.ac.uk/pdbsum/2cqh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cqh ProSAT], [https://www.topsan.org/Proteins/RSGI/2cqh TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/IF2B2_HUMAN IF2B2_HUMAN]] Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. May regulate translation of target mRNAs.<ref>PMID:9891060</ref>
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[https://www.uniprot.org/uniprot/IF2B2_HUMAN IF2B2_HUMAN] Binds to the 5'-UTR of the insulin-like growth factor 2 (IGF2) mRNAs. Binding is isoform-specific. May regulate translation of target mRNAs.<ref>PMID:9891060</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Inoue, M]]
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[[Category: Inoue M]]
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[[Category: Kigawa, T]]
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[[Category: Kigawa T]]
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[[Category: Muto, Y]]
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[[Category: Muto Y]]
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[[Category: Structural genomic]]
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[[Category: Shirouzu M]]
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[[Category: Shirouzu, M]]
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[[Category: Suzuki S]]
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[[Category: Suzuki, S]]
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[[Category: Terada T]]
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[[Category: Terada, T]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rbd]]
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[[Category: Rna binding domain]]
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[[Category: Rna binding protein]]
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[[Category: Rna recognition motif]]
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[[Category: Rnp]]
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[[Category: Rrm]]
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[[Category: Rsgi]]
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Current revision

Solution structure of the RNA binding domain of IGF-II mRNA-binding protein 2

PDB ID 2cqh

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