2cre

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Current revision (11:29, 22 May 2024) (edit) (undo)
 
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==Solution structure of RSGI RUH-036, an SH3 domain from human cDNA==
==Solution structure of RSGI RUH-036, an SH3 domain from human cDNA==
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<StructureSection load='2cre' size='340' side='right'caption='[[2cre]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2cre' size='340' side='right'caption='[[2cre]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2cre]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CRE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CRE FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2cre]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CRE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CRE FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cre OCA], [https://pdbe.org/2cre PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cre RCSB], [https://www.ebi.ac.uk/pdbsum/2cre PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cre ProSAT], [https://www.topsan.org/Proteins/RSGI/2cre TOPSAN]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cre OCA], [https://pdbe.org/2cre PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cre RCSB], [https://www.ebi.ac.uk/pdbsum/2cre PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cre ProSAT], [https://www.topsan.org/Proteins/RSGI/2cre TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/CASS4_HUMAN CASS4_HUMAN]] Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading.<ref>PMID:18256281</ref>
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[https://www.uniprot.org/uniprot/CASS4_HUMAN CASS4_HUMAN] Docking protein that plays a role in tyrosine kinase-based signaling related to cell adhesion and cell spreading. Regulates PTK2/FAK1 activity, focal adhesion integrity, and cell spreading.<ref>PMID:18256281</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Hayashi, F]]
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[[Category: Hayashi F]]
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[[Category: Hirota, H]]
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[[Category: Hirota H]]
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[[Category: Momen, A Z.M Ruhul]]
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[[Category: Ruhul Momen AZM]]
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[[Category: Structural genomic]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: Beta barrel]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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[[Category: Sh3 domain]]
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[[Category: Src homology 3 domain]]
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[[Category: Unknown function]]
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Current revision

Solution structure of RSGI RUH-036, an SH3 domain from human cDNA

PDB ID 2cre

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