2cx8

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<StructureSection load='2cx8' size='340' side='right'caption='[[2cx8]], [[Resolution|resolution]] 2.53&Aring;' scene=''>
<StructureSection load='2cx8' size='340' side='right'caption='[[2cx8]], [[Resolution|resolution]] 2.53&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2cx8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"flavobacterium_thermophilum"_yoshida_and_oshima_1971 "flavobacterium thermophilum" yoshida and oshima 1971]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CX8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CX8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2cx8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus Thermus thermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CX8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CX8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.53&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SAH:S-ADENOSYL-L-HOMOCYSTEINE'>SAH</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cx8 OCA], [https://pdbe.org/2cx8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cx8 RCSB], [https://www.ebi.ac.uk/pdbsum/2cx8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cx8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cx8 TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2cx8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2cx8 OCA], [https://pdbe.org/2cx8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2cx8 RCSB], [https://www.ebi.ac.uk/pdbsum/2cx8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2cx8 ProSAT], [https://www.topsan.org/Proteins/RSGI/2cx8 TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/Q5SKI6_THET8 Q5SKI6_THET8]] Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity).[PIRNR:PIRNR015601]
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[https://www.uniprot.org/uniprot/Q5SKI6_THET8 Q5SKI6_THET8] Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity).[PIRNR:PIRNR015601]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Flavobacterium thermophilum yoshida and oshima 1971]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Murayama, K]]
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[[Category: Thermus thermophilus]]
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[[Category: Structural genomic]]
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[[Category: Murayama K]]
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[[Category: Shirouzu, M]]
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[[Category: Shirouzu M]]
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[[Category: Yokoyama, S]]
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[[Category: Yokoyama S]]
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[[Category: Methyltransferase]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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[[Category: Transferase]]
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[[Category: Type iv]]
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Revision as of 11:32, 22 May 2024

Crystal structure of methyltransferase with ligand(SAH)

PDB ID 2cx8

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