2did
From Proteopedia
(Difference between revisions)
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==One sequence two fold ? : Correct fold of the zf-B-box domain from human tripartite motif protein 39== | ==One sequence two fold ? : Correct fold of the zf-B-box domain from human tripartite motif protein 39== | ||
| - | <StructureSection load='2did' size='340' side='right'caption='[[2did | + | <StructureSection load='2did' size='340' side='right'caption='[[2did]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2did]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2did]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2DID OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2DID FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2did FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2did OCA], [https://pdbe.org/2did PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2did RCSB], [https://www.ebi.ac.uk/pdbsum/2did PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2did ProSAT], [https://www.topsan.org/Proteins/RSGI/2did TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2did FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2did OCA], [https://pdbe.org/2did PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2did RCSB], [https://www.ebi.ac.uk/pdbsum/2did PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2did ProSAT], [https://www.topsan.org/Proteins/RSGI/2did TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/TRI39_HUMAN TRI39_HUMAN] E3 ubiquitin-protein ligase. May facilitate apoptosis by inhibiting APC/C-Cdh1-mediated poly-ubiquitination and subsequent proteasome-mediated degradation of the pro-apoptotic protein MOAP1.<ref>PMID:19100260</ref> <ref>PMID:22529100</ref> | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Inoue | + | [[Category: Inoue M]] |
| - | [[Category: Kigawa | + | [[Category: Kigawa T]] |
| - | [[Category: Koshiba | + | [[Category: Koshiba S]] |
| - | + | [[Category: Tomizawa T]] | |
| - | [[Category: Tomizawa | + | [[Category: Yokoyama S]] |
| - | [[Category: Yokoyama | + | |
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Current revision
One sequence two fold ? : Correct fold of the zf-B-box domain from human tripartite motif protein 39
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