Annexin
From Proteopedia
(Difference between revisions)
| Line 8: | Line 8: | ||
*'''Annexin V''' is the most abundant scaffolding protein. <br /> | *'''Annexin V''' is the most abundant scaffolding protein. <br /> | ||
*'''Annexin VI''' is involved in endocytosis and regulates entry of ligands to prelysosomal compartment<ref>PMID:10940299</ref>. <br /> | *'''Annexin VI''' is involved in endocytosis and regulates entry of ligands to prelysosomal compartment<ref>PMID:10940299</ref>. <br /> | ||
| + | *'''Annexin VIII''' is calcium-dependent phospholipid-binding involved in blood coagulation<ref>PMID:8018923</ref>. <br /> | ||
*'''Annexin E1''' (AnE1) is associated with tubulin in trophozoites of ''Giardia lamblia'' and forms local slubs in the flagella. <br /> | *'''Annexin E1''' (AnE1) is associated with tubulin in trophozoites of ''Giardia lamblia'' and forms local slubs in the flagella. <br /> | ||
*'''Annexin A-V''' has a major role in coagulation. <br /> | *'''Annexin A-V''' has a major role in coagulation. <br /> | ||
Current revision
| |||||||||||
References
- ↑ Lim LH, Pervaiz S. Annexin 1: the new face of an old molecule. FASEB J. 2007 Apr;21(4):968-75. PMID:17215481 doi:10.1096/fj.06-7464rev
- ↑ Sharma MC, Sharma M. The role of annexin II in angiogenesis and tumor progression: a potential therapeutic target. Curr Pharm Des. 2007;13(35):3568-75. PMID:18220793 doi:10.2174/138161207782794167
- ↑ Grewal T, Heeren J, Mewawala D, Schnitgerhans T, Wendt D, Salomon G, Enrich C, Beisiegel U, Jäckle S. Annexin VI stimulates endocytosis and is involved in the trafficking of low density lipoprotein to the prelysosomal compartment. J Biol Chem. 2000 Oct 27;275(43):33806-13. PMID:10940299 doi:10.1074/jbc.M002662200
- ↑ Sarkar A, Yang P, Fan YH, Mu ZM, Hauptmann R, Adolf GR, Stass SA, Chang KS. Regulation of the expression of annexin VIII in acute promyelocytic leukemia. Blood. 1994 Jul 1;84(1):279-86 PMID:8018923
- ↑ Mo Y, Campos B, Mealy TR, Commodore L, Head JF, Dedman JR, Seaton BA. Interfacial basic cluster in annexin V couples phospholipid binding and trimer formation on membrane surfaces. J Biol Chem. 2003 Jan 24;278(4):2437-43. Epub 2002 Oct 24. PMID:12401794 doi:10.1074/jbc.M210286200
