Antifreeze protein
From Proteopedia
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== Function == | == Function == | ||
| - | '''Antifreeze protein''' (AFP) permits the survival of certain organisms in subzero temperatures. AFP binds to small ice crystals thus inhibiting their growth.<ref>PMID:15152087</ref><br /> | + | '''Antifreeze protein''' (AFP) permits the survival of certain organisms in subzero temperatures. AFP binds to small ice crystals thus inhibiting their growth.<ref>PMID:15152087</ref>. There are 3 types of AFP which differ in the ice crusts face to which they bind<ref>PMID:33317024</ref>.<br /> |
| + | *'''AFP I''' is Ala-rich and alpha helical<br /> | ||
| + | *'''AFP II''' is Cys-rich and globular<br /> | ||
| + | *'''AFP III''' is globular<br /> | ||
* For winter flounder antifreeze protein type I see [[User:Mary Ball/AFP]].<br /> | * For winter flounder antifreeze protein type I see [[User:Mary Ball/AFP]].<br /> | ||
* For snow flea antifreeze protein see [[Sandox 2pne]] | * For snow flea antifreeze protein see [[Sandox 2pne]] | ||
Current revision
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References
- ↑ Jorov A, Zhorov BS, Yang DS. Theoretical study of interaction of winter flounder antifreeze protein with ice. Protein Sci. 2004 Jun;13(6):1524-37. PMID:15152087 doi:http://dx.doi.org/10.1110/ps.04641104
- ↑ Eskandari A, Leow TC, Rahman MBA, Oslan SN. Antifreeze Proteins and Their Practical Utilization in Industry, Medicine, and Agriculture. Biomolecules. 2020 Dec 9;10(12):1649. PMID:33317024 doi:10.3390/biom10121649
- ↑ Kondo H, Hanada Y, Sugimoto H, Hoshino T, Garnham CP, Davies PL, Tsuda S. Ice-binding site of snow mold fungus antifreeze protein deviates from structural regularity and high conservation. Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9360-5. Epub 2012 May 29. PMID:22645341 doi:10.1073/pnas.1121607109
