Arrestin
From Proteopedia
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*'''Arrestin-3''' assists in activation of JNK3 <ref>PMID:37371033</ref>. | *'''Arrestin-3''' assists in activation of JNK3 <ref>PMID:37371033</ref>. | ||
*'''Arrestin-4''' or '''cone arrestin''' binds in a cone cell th G protein kinase to desensitise opsin. | *'''Arrestin-4''' or '''cone arrestin''' binds in a cone cell th G protein kinase to desensitise opsin. | ||
| + | *'''S-arrestin''' binds to photo activated Rho and terminates its signaling. | ||
== Structural highlights == | == Structural highlights == | ||
Current revision
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References
- ↑ Hirsch JA, Schubert C, Gurevich VV, Sigler PB. The 2.8 A crystal structure of visual arrestin: a model for arrestin's regulation. Cell. 1999 Apr 16;97(2):257-69. PMID:10219246
- ↑ Zhu L, Almaça J, Dadi PK, Hong H, Sakamoto W, Rossi M, Lee RJ, Vierra NC, Lu H, Cui Y, McMillin SM, Perry NA, Gurevich VV, Lee A, Kuo B, Leapman RD, Matschinsky FM, Doliba NM, Urs NM, Caron MG, Jacobson DA, Caicedo A, Wess J. β-arrestin-2 is an essential regulator of pancreatic β-cell function under physiological and pathophysiological conditions. Nat Commun. 2017 Feb 1;8:14295. PMID:28145434 doi:10.1038/ncomms14295
- ↑ Zheng C, Weinstein LD, Nguyen KK, Grewal A, Gurevich EV, Gurevich VV. GPCR Binding and JNK3 Activation by Arrestin-3 Have Different Structural Requirements. Cells. 2023 Jun 6;12(12):1563. PMID:37371033 doi:10.3390/cells12121563
