2e1o
From Proteopedia
(Difference between revisions)
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==Solution structure of RSGI RUH-028, a homeobox domain from human cDNA== | ==Solution structure of RSGI RUH-028, a homeobox domain from human cDNA== | ||
| - | <StructureSection load='2e1o' size='340' side='right'caption='[[2e1o | + | <StructureSection load='2e1o' size='340' side='right'caption='[[2e1o]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2e1o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2e1o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=1wqi 1wqi]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E1O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E1O FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e1o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e1o OCA], [https://pdbe.org/2e1o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e1o RCSB], [https://www.ebi.ac.uk/pdbsum/2e1o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e1o ProSAT], [https://www.topsan.org/Proteins/RSGI/2e1o TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e1o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e1o OCA], [https://pdbe.org/2e1o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e1o RCSB], [https://www.ebi.ac.uk/pdbsum/2e1o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e1o ProSAT], [https://www.topsan.org/Proteins/RSGI/2e1o TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/HHEX_HUMAN HHEX_HUMAN] Recognizes the DNA sequence 5'-ATTAA-3'. Transcriptional repressor. May play a role in hematopoietic differentiation. Establishes anterior identity at two levels; acts early to enhance canonical WNT-signaling by repressing expression of TLE4, and acts later to inhibit NODAL-signaling by directly targeting NODAL (By similarity). | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Abe | + | [[Category: Abe T]] |
| - | [[Category: Hirota | + | [[Category: Hirota H]] |
| - | [[Category: Kawaii | + | [[Category: Kawaii S]] |
| - | [[Category: Kigawa | + | [[Category: Kigawa T]] |
| - | [[Category: Koshiba | + | [[Category: Koshiba S]] |
| - | [[Category: Nakamura | + | [[Category: Nakamura A]] |
| - | [[Category: Nameki | + | [[Category: Nameki N]] |
| - | [[Category: Ohnishi | + | [[Category: Ohnishi S]] |
| - | + | [[Category: Tochio N]] | |
| - | [[Category: Tochio | + | [[Category: Yokoyama S]] |
| - | [[Category: Yokoyama | + | |
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Current revision
Solution structure of RSGI RUH-028, a homeobox domain from human cDNA
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Categories: Homo sapiens | Large Structures | Abe T | Hirota H | Kawaii S | Kigawa T | Koshiba S | Nakamura A | Nameki N | Ohnishi S | Tochio N | Yokoyama S
