2e5z
From Proteopedia
(Difference between revisions)
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==Solution structure of the surp2 domain in splicing factor, arginine/serine-rich 8== | ==Solution structure of the surp2 domain in splicing factor, arginine/serine-rich 8== | ||
| - | <StructureSection load='2e5z' size='340' side='right'caption='[[2e5z | + | <StructureSection load='2e5z' size='340' side='right'caption='[[2e5z]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2e5z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2e5z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E5Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E5Z FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e5z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e5z OCA], [https://pdbe.org/2e5z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e5z RCSB], [https://www.ebi.ac.uk/pdbsum/2e5z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e5z ProSAT], [https://www.topsan.org/Proteins/RSGI/2e5z TOPSAN]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e5z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e5z OCA], [https://pdbe.org/2e5z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e5z RCSB], [https://www.ebi.ac.uk/pdbsum/2e5z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e5z ProSAT], [https://www.topsan.org/Proteins/RSGI/2e5z TOPSAN]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SFSWA_HUMAN SFSWA_HUMAN] Plays a role as an alternative splicing regulator. Regulate its own expression at the level of RNA processing. Also regulates the splicing of fibronectin and CD45 genes. May act, at least in part, by interaction with other R/S-containing splicing factors. Represses the splicing of MAPT/Tau exon 10.<ref>PMID:8940107</ref> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e5z ConSurf]. | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e5z ConSurf]. | ||
<div style="clear:both"></div> | <div style="clear:both"></div> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: He | + | [[Category: He F]] |
| - | [[Category: Inoue | + | [[Category: Inoue M]] |
| - | [[Category: Kigawa | + | [[Category: Kigawa T]] |
| - | [[Category: Muto | + | [[Category: Muto Y]] |
| - | + | [[Category: Shirouzu M]] | |
| - | [[Category: Shirouzu | + | [[Category: Terada T]] |
| - | [[Category: Terada | + | [[Category: Yokoyama S]] |
| - | [[Category: Yokoyama | + | |
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Current revision
Solution structure of the surp2 domain in splicing factor, arginine/serine-rich 8
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Categories: Homo sapiens | Large Structures | He F | Inoue M | Kigawa T | Muto Y | Shirouzu M | Terada T | Yokoyama S
