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2edn

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Current revision (18:49, 29 May 2024) (edit) (undo)
 
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==Solution structure of the first ig-like domain from human Myosin-binding protein C, fast-type==
==Solution structure of the first ig-like domain from human Myosin-binding protein C, fast-type==
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<StructureSection load='2edn' size='340' side='right'caption='[[2edn]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2edn' size='340' side='right'caption='[[2edn]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2edn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EDN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EDN FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2edn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EDN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EDN FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MYBPC2, MYBPCF ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2edn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2edn OCA], [https://pdbe.org/2edn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2edn RCSB], [https://www.ebi.ac.uk/pdbsum/2edn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2edn ProSAT], [https://www.topsan.org/Proteins/RSGI/2edn TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2edn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2edn OCA], [https://pdbe.org/2edn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2edn RCSB], [https://www.ebi.ac.uk/pdbsum/2edn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2edn ProSAT], [https://www.topsan.org/Proteins/RSGI/2edn TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MYPC2_HUMAN MYPC2_HUMAN]] Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
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[https://www.uniprot.org/uniprot/MYPC2_HUMAN MYPC2_HUMAN] Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Hayashi, F]]
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[[Category: Hayashi F]]
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[[Category: Kurosaki, C]]
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[[Category: Kurosaki C]]
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[[Category: Nagashima, K]]
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[[Category: Nagashima K]]
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[[Category: Structural genomic]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: Yoshida M]]
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[[Category: Yoshida, M]]
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[[Category: Beta-sandwich]]
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[[Category: C-protein]]
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[[Category: Contractile protein]]
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[[Category: Fast mybp-c]]
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[[Category: Ig-fold]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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[[Category: Skeletal muscle fast isoform]]
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Current revision

Solution structure of the first ig-like domain from human Myosin-binding protein C, fast-type

PDB ID 2edn

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