2emc

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (18:52, 29 May 2024) (edit) (undo)
 
Line 1: Line 1:
==Solution structure of the C2H2 type zinc finger (region 641-673) of human Zinc finger protein 473==
==Solution structure of the C2H2 type zinc finger (region 641-673) of human Zinc finger protein 473==
-
<StructureSection load='2emc' size='340' side='right'caption='[[2emc]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
+
<StructureSection load='2emc' size='340' side='right'caption='[[2emc]]' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2emc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EMC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EMC FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2emc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2EMC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2EMC FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZNF473 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2emc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2emc OCA], [https://pdbe.org/2emc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2emc RCSB], [https://www.ebi.ac.uk/pdbsum/2emc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2emc ProSAT], [https://www.topsan.org/Proteins/RSGI/2emc TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2emc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2emc OCA], [https://pdbe.org/2emc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2emc RCSB], [https://www.ebi.ac.uk/pdbsum/2emc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2emc ProSAT], [https://www.topsan.org/Proteins/RSGI/2emc TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/ZN473_HUMAN ZN473_HUMAN]] Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases.<ref>PMID:11782445</ref> <ref>PMID:16914750</ref> <ref>PMID:16714279</ref>
+
[https://www.uniprot.org/uniprot/ZN473_HUMAN ZN473_HUMAN] Involved in histone 3'-end pre-mRNA processing by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex. Increases histone 3'-end pre-mRNA processing but has no effect on U7 snRNP levels, when overexpressed. Required for cell cycle progression from G1 to S phases.<ref>PMID:11782445</ref> <ref>PMID:16914750</ref> <ref>PMID:16714279</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 24: Line 24:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Abe, H]]
+
[[Category: Abe H]]
-
[[Category: Kigawa, T]]
+
[[Category: Kigawa T]]
-
[[Category: Kobayashi, N]]
+
[[Category: Kobayashi N]]
-
[[Category: Koshiba, S]]
+
[[Category: Koshiba S]]
-
[[Category: Li, H]]
+
[[Category: Li H]]
-
[[Category: Structural genomic]]
+
[[Category: Saito K]]
-
[[Category: Saito, K]]
+
[[Category: Sato M]]
-
[[Category: Sato, M]]
+
[[Category: Tochio N]]
-
[[Category: Tochio, N]]
+
[[Category: Tomizawa T]]
-
[[Category: Tomizawa, T]]
+
[[Category: Yokoyama S]]
-
[[Category: Yokoyama, S]]
+
-
[[Category: National project on protein structural and functional analyse]]
+
-
[[Category: Nppsfa]]
+
-
[[Category: Rsgi]]
+
-
[[Category: Transcription]]
+
-
[[Category: Zf-c2h2]]
+

Current revision

Solution structure of the C2H2 type zinc finger (region 641-673) of human Zinc finger protein 473

PDB ID 2emc

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2emc"
Personal tools