2kjy

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Current revision (19:12, 29 May 2024) (edit) (undo)
 
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==MYPT1(658-714)==
==MYPT1(658-714)==
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<StructureSection load='2kjy' size='340' side='right'caption='[[2kjy]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2kjy' size='340' side='right'caption='[[2kjy]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2kjy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KJY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2kjy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KJY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KJY FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PPP1R12A, MBS, MYPT1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kjy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kjy OCA], [https://pdbe.org/2kjy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kjy RCSB], [https://www.ebi.ac.uk/pdbsum/2kjy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kjy ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kjy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kjy OCA], [https://pdbe.org/2kjy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kjy RCSB], [https://www.ebi.ac.uk/pdbsum/2kjy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kjy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/MYPT1_HUMAN MYPT1_HUMAN]] Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.<ref>PMID:19245366</ref> <ref>PMID:18477460</ref> <ref>PMID:20354225</ref>
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[https://www.uniprot.org/uniprot/MYPT1_HUMAN MYPT1_HUMAN] Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.<ref>PMID:19245366</ref> <ref>PMID:18477460</ref> <ref>PMID:20354225</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Eto, M]]
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[[Category: Eto M]]
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[[Category: Iwaoka, R]]
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[[Category: Iwaoka R]]
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[[Category: Mori, S]]
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[[Category: Mori S]]
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[[Category: Ohki, S]]
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[[Category: Ohki S]]
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[[Category: Alternative splicing]]
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[[Category: Ank repeat]]
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[[Category: Cytoplasm]]
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[[Category: Myosin phosphatase]]
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[[Category: Mypt1]]
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[[Category: Phosphoprotein]]
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[[Category: Phosphorylation]]
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[[Category: Polymorphism]]
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[[Category: Protein phosphatase 1]]
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[[Category: Signaling protein]]
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Current revision

MYPT1(658-714)

PDB ID 2kjy

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Proteopedia Page Contributors and Editors (what is this?)

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