2rpz

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Current revision (19:15, 29 May 2024) (edit) (undo)
 
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==Solution structure of the monomeric form of mouse APOBEC2==
==Solution structure of the monomeric form of mouse APOBEC2==
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<StructureSection load='2rpz' size='340' side='right'caption='[[2rpz]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='2rpz' size='340' side='right'caption='[[2rpz]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2rpz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RPZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RPZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2rpz]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2RPZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2RPZ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rpz OCA], [https://pdbe.org/2rpz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rpz RCSB], [https://www.ebi.ac.uk/pdbsum/2rpz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rpz ProSAT], [https://www.topsan.org/Proteins/RSGI/2rpz TOPSAN]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2rpz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2rpz OCA], [https://pdbe.org/2rpz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2rpz RCSB], [https://www.ebi.ac.uk/pdbsum/2rpz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2rpz ProSAT], [https://www.topsan.org/Proteins/RSGI/2rpz TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/ABEC2_MOUSE ABEC2_MOUSE]] Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation (By similarity).
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[https://www.uniprot.org/uniprot/ABEC2_MOUSE ABEC2_MOUSE] Probable C to U editing enzyme whose physiological substrate is not yet known. Does not display detectable apoB mRNA editing. Has a low intrinsic cytidine deaminase activity. May play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Lk3 transgenic mice]]
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[[Category: Mus musculus]]
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[[Category: Hayashi, F]]
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[[Category: Hayashi F]]
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[[Category: Inoue, M]]
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[[Category: Inoue M]]
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[[Category: Kigawa, T]]
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[[Category: Kigawa T]]
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[[Category: Muto, Y]]
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[[Category: Muto Y]]
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[[Category: Nagashima, T]]
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[[Category: Nagashima T]]
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[[Category: Nagata, T]]
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[[Category: Nagata T]]
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[[Category: Structural genomic]]
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[[Category: Yokoyama S]]
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[[Category: Yokoyama, S]]
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[[Category: Cytidine deaminase]]
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[[Category: Hydrolase]]
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[[Category: Metal-binding]]
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[[Category: Mrna processing]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: Nppsfa]]
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[[Category: Rsgi]]
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[[Category: Zinc]]
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Current revision

Solution structure of the monomeric form of mouse APOBEC2

PDB ID 2rpz

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