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3jtp
From Proteopedia
(Difference between revisions)
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<StructureSection load='3jtp' size='340' side='right'caption='[[3jtp]], [[Resolution|resolution]] 2.17Å' scene=''> | <StructureSection load='3jtp' size='340' side='right'caption='[[3jtp]], [[Resolution|resolution]] 2.17Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[3jtp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3jtp]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3JTP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3JTP FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.17Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jtp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jtp OCA], [https://pdbe.org/3jtp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jtp RCSB], [https://www.ebi.ac.uk/pdbsum/3jtp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jtp ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3jtp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3jtp OCA], [https://pdbe.org/3jtp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3jtp RCSB], [https://www.ebi.ac.uk/pdbsum/3jtp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3jtp ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/MECA1_BACSU MECA1_BACSU] Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. Acts negatively in the development of competence by binding ComK and recruiting it to the ClpCP protease. When overexpressed, inhibits sporulation. Also involved in Spx degradation by ClpC.<ref>PMID:12598648</ref> | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Bacillus subtilis]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Mei | + | [[Category: Mei Z]] |
| - | [[Category: Qi | + | [[Category: Qi Y]] |
| - | [[Category: Shi | + | [[Category: Shi Y]] |
| - | [[Category: Wang | + | [[Category: Wang F]] |
| - | [[Category: Wang | + | [[Category: Wang J]] |
| - | [[Category: Yan | + | [[Category: Yan C]] |
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Current revision
crystal structure of the C-terminal domain of MecA
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Categories: Bacillus subtilis | Large Structures | Mei Z | Qi Y | Shi Y | Wang F | Wang J | Yan C

