6m31

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==Structural and Functional Insights into an Archaeal Lipid Synthase==
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==Structural and functional insights into an Archaeal synthase==
<StructureSection load='6m31' size='340' side='right'caption='[[6m31]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='6m31' size='340' side='right'caption='[[6m31]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6m31]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Metja Metja]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M31 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6M31 FirstGlance]. <br>
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6M31 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6M31 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPG:[(Z)-OCTADEC-9-ENYL]+(2R)-2,3-BIS(OXIDANYL)PROPANOATE'>MPG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MJ0279 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=243232 METJA])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=LDA:LAURYL+DIMETHYLAMINE-N-OXIDE'>LDA</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPG:[(Z)-OCTADEC-9-ENYL]+(2R)-2,3-BIS(OXIDANYL)PROPANOATE'>MPG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Geranylgeranylglycerol-phosphate_geranylgeranyltransferase Geranylgeranylglycerol-phosphate geranylgeranyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.5.1.42 2.5.1.42] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6m31 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m31 OCA], [https://pdbe.org/6m31 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6m31 RCSB], [https://www.ebi.ac.uk/pdbsum/6m31 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6m31 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6m31 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6m31 OCA], [https://pdbe.org/6m31 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6m31 RCSB], [https://www.ebi.ac.uk/pdbsum/6m31 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6m31 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
 
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[[https://www.uniprot.org/uniprot/DGGGP_METJA DGGGP_METJA]] Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids.
 
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Geranylgeranylglycerol-phosphate geranylgeranyltransferase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Metja]]
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[[Category: Sixue R]]
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[[Category: Cheng, W]]
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[[Category: Wei C]]
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[[Category: Ren, S]]
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[[Category: Lipid]]
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[[Category: Membrane protein]]
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Structural and functional insights into an Archaeal synthase

PDB ID 6m31

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