This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8i8m
From Proteopedia
(Difference between revisions)
| Line 4: | Line 4: | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[8i8m]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacter_sp._638 Enterobacter sp. 638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8I8M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8I8M FirstGlance]. <br> | <table><tr><td colspan='2'>[[8i8m]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterobacter_sp._638 Enterobacter sp. 638]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8I8M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8I8M FirstGlance]. <br> | ||
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PAE:PHOSPHONOACETIC+ACID'>PAE</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.651Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PAE:PHOSPHONOACETIC+ACID'>PAE</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8i8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8i8m OCA], [https://pdbe.org/8i8m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8i8m RCSB], [https://www.ebi.ac.uk/pdbsum/8i8m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8i8m ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8i8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8i8m OCA], [https://pdbe.org/8i8m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8i8m RCSB], [https://www.ebi.ac.uk/pdbsum/8i8m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8i8m ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [https://www.uniprot.org/uniprot/COAD_ENT38 COAD_ENT38] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. | + | [https://www.uniprot.org/uniprot/COAD_ENT38 COAD_ENT38] Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.[HAMAP-Rule:MF_00151] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Current revision
Crystal structure of the ternary complex of Phosphopantetheine adenylyltransferase (PPAT) from Enterobacter sp. with Coenzyme-A and Phosphonoacetic acid at 2.65 A resolution.
| |||||||||||
