Chromodomain-helicase-DNA-binding protein

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (09:53, 3 June 2024) (edit) (undo)
 
Line 4: Line 4:
* '''CHD1''' - ATP-dependent chromatin-modeling factor. Functions as substrate recognition component of the transcription regulatory acetylation complex SAGA.<br />
* '''CHD1''' - ATP-dependent chromatin-modeling factor. Functions as substrate recognition component of the transcription regulatory acetylation complex SAGA.<br />
* '''CHD4''' - Chromatin-modeling factor. Functions as component of the transcription regulatory deacetylation complex NuRD. See [[Chromodomain helicase DNA-binding factor 4 (CHD4)]].<br />
* '''CHD4''' - Chromatin-modeling factor. Functions as component of the transcription regulatory deacetylation complex NuRD. See [[Chromodomain helicase DNA-binding factor 4 (CHD4)]].<br />
 +
* '''CHD5''' - belongs to ATP-dependent chromatin remodelling proteins. It is a regulator of a tutor-suppressive network<ref>PMID:27096031</ref>.<br />
* '''CHD6''' - Probable transcription regulator.<br />
* '''CHD6''' - Probable transcription regulator.<br />
* '''CHD7''' - ATP-dependent chromatin-modeling factor. May be involved in the 45S precursor ribosomal RNA production.<br />
* '''CHD7''' - ATP-dependent chromatin-modeling factor. May be involved in the 45S precursor ribosomal RNA production.<br />

Current revision

Tandem chromodomains of human CHD1 (grey, green, pink) complex with histone H3 tail peptide (yellow) containing trimethyllysine and dimethylarginine (PDB entry 2b2u)

Drag the structure with the mouse to rotate

References

  1. Woodage T, Basrai MA, Baxevanis AD, Hieter P, Collins FS. Characterization of the CHD family of proteins. Proc Natl Acad Sci U S A. 1997 Oct 14;94(21):11472-7. PMID:9326634
  2. Seldon CS, Colbert LE, Hall WA, Fisher SB, Yu DS, Landry JC. Chromodomain-helicase-DNA binding protein 5, 7 and pronecrotic mixed lineage kinase domain-like protein serve as potential prognostic biomarkers in patients with resected pancreatic adenocarcinomas. World J Gastrointest Oncol. 2016 Apr 15;8(4):358-65. PMID:27096031 doi:10.4251/wjgo.v8.i4.358

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

Personal tools