5est

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<StructureSection load='5est' size='340' side='right'caption='[[5est]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
<StructureSection load='5est' size='340' side='right'caption='[[5est]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5est]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EST OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5EST FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5est]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EST OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EST FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0P2:N~2~-[(BENZYLOXY)CARBONYL]-N-[(1R,2S)-1-(DIHYDROXYBORANYL)-2-METHYLBUTYL]-L-ALANINAMIDE'>0P2</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pancreatic_elastase Pancreatic elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.36 3.4.21.36] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0P2:N~2~-[(BENZYLOXY)CARBONYL]-N-[(1R,2S)-1-(DIHYDROXYBORANYL)-2-METHYLBUTYL]-L-ALANINAMIDE'>0P2</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5est FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5est OCA], [http://pdbe.org/5est PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5est RCSB], [http://www.ebi.ac.uk/pdbsum/5est PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5est ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5est FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5est OCA], [https://pdbe.org/5est PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5est RCSB], [https://www.ebi.ac.uk/pdbsum/5est PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5est ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CELA1_PIG CELA1_PIG]] Acts upon elastin.
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[https://www.uniprot.org/uniprot/CELA1_PIG CELA1_PIG] Acts upon elastin.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pancreatic elastase]]
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[[Category: Sus scrofa]]
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[[Category: Pig]]
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[[Category: Meyerjunior EF]]
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[[Category: Meyerjunior, E F]]
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[[Category: Radhakrishnan R]]
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[[Category: Radhakrishnan, R]]
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[[Category: Rosenfieldjunior RE]]
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[[Category: Rosenfieldjunior, R E]]
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[[Category: Takahashi LH]]
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[[Category: Takahashi, L H]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Serine proteinase]]
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Revision as of 05:41, 5 June 2024

Crystallographic analysis of the inhibition of porcine pancreatic elastase by a peptidyl boronic acid: structure of a reaction intermediate

PDB ID 5est

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