7roc

<table><tr><td colspan='2'>[[7roc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sulfolobus_monocaudavirus_smv1 Sulfolobus monocaudavirus smv1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ROC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ROC FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7roc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7roc OCA], [https://pdbe.org/7roc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7roc RCSB], [https://www.ebi.ac.uk/pdbsum/7roc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7roc ProSAT]</span></td></tr>

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== Publication Abstract from PubMed ==

Spindle- or lemon-shaped viruses infect archaea in diverse environments. Due to the highly pleomorphic nature of these virions, which can be found with cylindrical tails emanating from the spindle-shaped body, structural studies of these capsids have been challenging. We have determined the atomic structure of the capsid of Sulfolobus monocaudavirus 1, a virus that infects hosts living in nearly boiling acid. A highly hydrophobic protein, likely integrated into the host membrane before the virions assemble, forms 7 strands that slide past each other in both the tails and the spindle body. We observe the discrete steps that occur as the tail tubes expand, and these are due to highly conserved quasiequivalent interactions with neighboring subunits maintained despite significant diameter changes. Our results show how helical assemblies can vary their diameters, becoming nearly spherical to package a larger genome and suggest how all spindle-shaped viruses have evolved from archaeal rod-like viruses.

Spindle-shaped archaeal viruses evolved from rod-shaped ancestors to package a larger genome.,Wang F, Cvirkaite-Krupovic V, Vos M, Beltran LC, Kreutzberger MAB, Winter JM, Su Z, Liu J, Schouten S, Krupovic M, Egelman EH Cell. 2022 Mar 17. pii: S0092-8674(22)00199-4. doi: 10.1016/j.cell.2022.02.019. PMID:35325592<ref>PMID:35325592</ref>

From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>

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<div class="pdbe-citations 7roc" style="background-color:#fffaf0;"></div>

== References ==

<references/>

[[Category: Cvirkaite-Krupovic, V]]

[[Category: Egelman, E H]]

[[Category: Krupovic, M]]

[[Category: Wang, F]]

[[Category: Virus]]